Though it is difficult to predict the future, it is safe to say that collaborative, cross-disciplinary approaches to complex societal problems are here to stay. This is evidenced by team science, a collaborative and cross-disciplinary approach that has accomplished biomedical breakthroughs once considered impossible. Making the most of the opportunities that team science has to offer may seem fraught with the challenges of adapting from a solo-investigator culture to one of collaboration; however, new advances become possible through this methodology.